As per our Business Plan for the current phase of the CBTBR, the following services were provided in 2012:
The provision of scientific/ technical service, advice and assistance to local Government, regional services, institutions, research groups and individuals
- Dr. Kana examined a PhD thesis for Stellenbosch University and an MSc Dissertation for WITS University.
- Dr. Warner examined a PhD thesis for the University of Oslo, Norway, and will travel to Norway in 2013 for the examination viva. Dr. Williams examined a PhD thesis submitted to Stellenbosch University and Dr. Evans examined Honours projects submitted to UCT.
- Numerous external examinations were done by members of the SU node. These include examining PhD or MSc theses for WITS, Pretoria, UCT, UWC and other universities and Universities of Technology. Details are not kept.
Journal editing and reviews
- Dr Kana reviewed manuscripts for Antimicrobial Agents and Chemotherapy, PLoS One, PLoS Pathogens, Tuberculosis, Antonie van Leeuwenhoek Journal of Microbiology, The Journal of Infectious Diseases, Vaccine, Molecular and Cellular Biochemistry.
- Prof. Mizrahi served on the Editorial Advisory Boards of the Biochemical Journal, Tuberculosis, Cellular Microbiology, and the Editorial Board of Emerging Microbes and Infection. In 2012, she also reviewed manuscripts submitted to Nature Genetics, E-Life, PLoS Pathogens, and Cell Host & Microbe.
- Dr. Warner reviewed manuscripts submitted to PNAS, PLoS Pathogens, Molecular Microbiology, Tuberculosis, Journal of Infectious Diseases, Journal of Clinical Microbiology, PLoS One and Journal of Infectious Diseases. Dr. Abrahams reviewed a manuscript for PLoS One.
- Most if not all senior members of the SU node review numerous manuscripts for international journals. Records are not kept, but journals include Nature Reviews, Lancet, Lancet Infectious Diseases, PLoS, J Antimicrobial Chemotherapy, J Mol Med, BMC, Tuberculosis, IJTLD, JID, J Biotech, IJMS, Indian Heart Journal, Cardiovasc. J SA, J Biotech, IJMS, Molecular Biology and Evolution, Journal of Infection in Developing Countries, Journal of Bacteriology, Journal of Medical Microbiology, American Journal of Respiratory Critical Care Medicine, Tuberculosis and Journal of Molecular Biology and Biotechnology.
Expert Panel or Committee Membership
- Dr. Kana served on the Advisory Committee of the CU-SA Fogarty AITRP.
- Dr. Kana served on the Steering Committee for the Wits-Aurum Coalition and chairs the Projects Committee for this venture
- Dr. Kana served on the University Research Council (URC) at Wits University
- Dr. Kana and Dr. Gordhan served on the Faculty Research Council (FRC), Faculty of Health Sciences Wits University
- Dr. Kana and Dr. Gordhan served on the Postgraduate Committee, Faculty of Health Sciences Wits University
- Dr. Gordhan served on the Research Entity Review Task Group, Faculty of Health Sciences Wits University
- Dr. Kana chaired the Wits Health Sciences Research Day Committee (2012)
- Dr. Kana was elected to serve on the FRC Budget task group, Faculty of Health Sciences Wits University
- Dr. Kana served on the Faculty Advisory Board, Faculty of Health Sciences Wits University
- Dr. Kana served on the Executive Committee of the School of Pathology, Faculty of Health Sciences Wits University
- Dr. Kana served on the Research Entity Forum, Faculty of Health Sciences Wits University
- Dr. Kana served on the Faculty of Health Sciences Research Equipment Review Committee, Wits University
- Dr. Kana served on the URC major and minor Equipment Review Committees, Wits University
- Dr. Kana served on the Research Coordinators Committee, Faculty of Health Sciences, Wits University
- Dr. Kana served on the Faculty of Health Sciences Imaging Committee, Wits University
- Dr. Kana served on the Faculty Graduate Studies Committee Working Group on Research Output Guidelines, Faculty of Health Sciences, Wits University
- Dr. Kana served on the Molecular Biosciences Thrust Committee, Faculty of Health Sciences, Wits University
- Dr Gordhan served on the BTC Scholarship Selection Committee
- Dr Gordhan served on the NRF Postdoctoral review Committee
- Prof. Mizrahi served as a member of the Board of Directors, KwaZulu Natal Research Institute for TB and HIV (K-RITH), University of KwaZulu Natal, South Africa
- Prof. Mizrahi served on the Council of Scientific Advisors of the International Centre for Genetic Engineering and Biotechnology (Trieste, Italy)
- Prof. Mizrahi served as a member of the Scientific Advisory Board of K-RITH, University of KwaZulu Natal
- Prof. Mizrahi served on the Search Committee of K-RITH, University of KwaZulu Natal
- Prof. Mizrahi served as a member of the Scientific Advisory Committee of the Global Alliance for TB Drug Development (TB Alliance, New York)
- Prof. Mizrahi served as a member of the SACEMA Trust and also as a member of the SACEMA Management Board, Stellenbosch University
- Prof. Mizrahi was appointed to, and served on the Visiting Scholars Fund Committee, UCT
- Prof. Mizrahi served on the Research Funding Task-Team of the University Research Committee, UCT
- Prof. Mizrahi served on the Internationalisation Task Team of the University Research Committee, UCT
- Prof. Mizrahi served on the Area Stakeholders Committee, Carnegie Corporation Developing the Next Generation Academics Programme, UCT
- Prof. Mizrahi chaired the Executive Committee of the IIDMM, UCT
- Prof Mizrahi chaired the Membership Committee of the IIDMM, UCT
- Prof. Mizrahi was appointed to the Senior Council on Research, Faculty of Health Sciences, UCT
- Dr. Warner served as a member of the Steering Committee, iThemba Pharmaceuticals, Johannesburg
- Dr. Warner served as a member of the Institutional Biosafety Committee, UCT
- Dr. Warner served as a member of the GMO Committee, UCT
- Dr. Warner served as the MMRU Hazardous Chemical Coordinator, IIDMM, UCT
- Dr. Warner served as the Lead Academic in charge of the WBS Level 2 Biological Safety Level III laboratory, IIDMM, UCT
- Dr. Warner served on the Integrated Education Committee of the IIDMM, UCT
- Dr. Warner served on the Abstract Review Committee of the 3rd SA TB Conference (TB/HIV Integration Conference), Durban, 12-15 June 2012
- Dr. Evans served on the Health & Safety Committee of the IIDMM, UCT
- Ms. Moosa served on Operations and Laboratory Management Committee of the IIDMM
- Dr. Evans chaired the UCT Health Sciences Postdoctoral Association (HSPDA) and Drs. Gopinath and Singh served on the leadership committee of the HSPDA.
- Ms. Koch served on the UCT Health Sciences Faculty Postgraduate Students Council (HSPSC) and headed the Social Responsiveness portfolio.
- Profs van Helden and Walzl served on MSF, GATB, WHO and Stop TB Partnership.
- Profs Walzl and Wiid served on the Ethics Committee for Experimental Animal Research of Stellenbosch University.
- Prof Warren served on the Centre for Infectious Diseases of Stellenbosch University.
- Profs Walzl and Warren served on the Research Committee of Stellenbosch University, Health Sciences.
- Prof Gey van Pittius served on the Committee for Postgraduate Education and Health Research Ethics Committee of Stellenbosch University Faculty of Health Sciences.
Examples of Research Funding Reviews
- Dr. Kana served as a reviewer for MRC Career Award Applications, NRF Rating and Evaluation program, NRF postdoctoral program and the NRF SA-France research program. Dr Kana also served as an external reviewer for the Portuguese Foundation for Science and Technology – 2012 Investigator Program. Dr Gordhan was part of a panel at the NRF post-doctoral and PDP workshop where she gave input on the NRF review process for fellowships and discussed some of the common mistakes and omissions on the applications. Dr Gordhan also assisted with the selection of the Postgraduate Degrees Awards for the best MSc and PhD thesis submitted to the Faculty of Health Sciences, Wits University for 2012. Both Dr. Gordhan and Dr. Kana served on assessor committees at Wits University for MSc and PhD proposals. Dr. Gordhan reviewed an application for the NHLS Research Trust grant program.
- Prof. Mizrahi served as a reviewer for the Wellcome Trust, the Bill & Melinda Gates Foundation and Seattle Biomed. She also served as a reviewer for promotion at the University of the Witwatersrand. Dr. Warner reviewed grant applications submitted to the Wellcome Trust, the NRF, and the MRC. He also served as an internal reviewer for numerous research proposals considered by the IIDMM Research Committee.
- Many of the SU node members are either on editorial boards or act as regular reviewers for many journals. Again, a list is not provided, since we have so many of these we do not keep record.
Other services rendered
- Dr Gordhan and Dr Kana reviewed abstracts submitted for the MRC Early Career Scientists Conference 2012, 24th – 25th October 2012.
- Dr Gordhan was invited to participate in the DST Scientific meeting: India-South African bilateral meeting, 21st -22nd February 2012.
- Speciation of Non Tuberculous Mycobacteria (NTM) for Kruger National Park
- Genotyping of clinical isolates (RFLP or mutation detection) for the NHLS and MSF.
- Prof V Corfield was NRF rating panel moderator in 2012
- Specialist diagnostic service for MDR or XDR TB cases
- Specialist diagnostic service for suspect extra-pulmonary TB cases
- Hospital medical specialist clinical services, e.g. pulmonology and genetics
- Weekly tutorials/practicals to Clinical Genetics registrars in molecular genetics by CBTBR staff during 2012 (Prof Corfield and Mrs de Villiers).
- Seegene (Korea): We are currently in a collaborative venture with Seegene, Inc. to design and improve M. tuberculosis diagnostics. Seegene is a molecular diagnostic company based in Korea well known for its pioneering R & D activities and novel technologies. Seegene has enhanced the sensitivity and specificity of PCR (polymerase chain reaction) that enables them to provide multiplex PCR products by which multiple target genes of pathogens can be simultaneously detected, saving time and cost.
- AID (Germany): Evaluation of a genetic drug susceptibility test.
- Hain Life Sciences (Germany): Evaluation of the MDRTBsl genetic drug susceptibility test.
- Vakzine Project Management (VPM): phase IIa vaccine trial on tuberculosis
- Cellestis: Evaluation of new peptide to diagnose TB
6. Gender impact of research
“Science for Women” (gender-sensitivity of the research agenda)
The work being undertaken in the CBTBR is aimed at contributing towards global efforts in researching and developing new laboratory-based tools for reducing the societal burden of TB. TB is the greatest single infectious cause of death in young women, and causes more deaths among women than all causes of maternal mortality combined. The particularly high rates of HIV co-infection in women are expected to fuel an increased prevalence of TB in women over time. In addition to the disease burden, TB also imposes a massive, but largely hidden burden of social impact on women.
“Science by Women” (the participation by women in the research programme)
Five out of the 13 Core Team Members of the CBTBR are women. In 2012, the CBTBR has also maintained a high percentage of female students (69% of all students and 57% of postdoctoral fellows), which is in line with demographic norms for the Life and Health Sciences at a national level. All three nodes have demonstrated that they are able to provide an environment which is attractive to, and supportive of women researchers at all levels, from Honours students to senior postdoctoral fellows and Core Team Members. These indicators confirm that the CBTBR serves as a centre in which women researchers are nurtured and developed.