The following technical service, advice and assistance to local Government, regional services, institutions, research groups and individuals was provided in 2016:
Thesis examination - click to open or close information
- Prof. Warner served as external examiner of a PhD submitted to the University of the Witwatersrand.
- Prof. Kana served as an external examiner for a PhD dissertations submitted to the University of Zimbabwe, Stellenbosch University and the University of KwaZulu Natal.
- Prof. Kana served as an external examiner for two MSc dissertations submitted to the University of KwaZulu Natal. Dr. Gordhan served as an external examiner an MSc dissertation submitted to the University of KwaZulu Natal.
- Prof. Kana served as an internal examiner for a PhD dissertation submitted to the University of the Witwatersrand.
- Prof. Walzl served as internal examiner for a PhD thesis from the Division of Virology.
- Dr. Loxton served as an external examiner for an MSc thesis from UKZN.
- Dr. Loxton served as an internal examiner for a PhD thesis from SU.
- Dr. Baker served as an internal examiner for a PhD thesis from the Department of Biomedical Sciences.
- Dr. Möller served as an internal examiner for a MSc thesis from the Division of Molecular Biology and Human Genetics.
- Dr. Kinnear served as an internal examiner for a MSc and PhD dissertations from the Division of Molecular Biology and Human Genetics.
- Dr. Kinnear served as an external examiner for a MSc thesis from the University of Kwazulu-Natal.
- Dr. Mouton served as an internal examiner of a MSc thesis of Mr. Bowker entitled, “Deciphering genetic susceptibility to tuberculosis meningitis” (supervised by Dr. Möller and Dr. Kinnear, SU).
Journal editing and reviews
- Prof. Mizrahi served on the Editorial Advisory Boards of Tuberculosis and Cellular Microbiology, and on the Editorial Boards of Current Opinion in Microbiology; Pathogens & Disease; Emerging Microbes and Infection and Cell Chemical Biology and was appointed to the Editorial Advisory Boards of ACS Central Science, ACS Infectious Diseases and Genome Medicine. Prof. Warner served on the Editorial Board of PLoS One, and as guest editor for mBio.
- Members of the UCT node reviewed manuscripts submitted to Science; PLoS Pathogens; PNAS; Clinical Infectious Diseases; Cell Chemical Biology; ACS Infectious Diseases; Antimicrobial Agents and Chemotherapy; American Journal for Respiratory and Critical Care Medicine; Faculty of 1000; mBio; Infection Genetics and Evolution; Trends in Pharmacological Sciences; Tuberculosis; Acta Dermato-Venereologica.
- Prof. Kana or Dr. Gordhan reviewed manuscripts for eLife, mBIO, BMC Public Health, Current Pharmaceutical Design, FEMS Microbiology Letters, PLoS One, Scientific Reports, Mutation Research and Journal of Infectious Diseases.
- Ms. Caroline Pule, Peer Reviewer of Abstracts submitted for the 47th Union World Conference on Lung Health, held in Liverpool in Liverpool, UK
- Prof. Miller M Associate editor for Journal of Zoo and Wildlife Medicine 2016.
- Prof. Miller M Reviewer for Emerging Infectious Diseases, American Journal of Veterinary Research, Journal of Wildlife Diseases, Journal of Zoo and Wildlife Medicine 2016.
- Mujuru TN Assistant at the Annual Academic Day 2016.
- Prof. Bardien Session chair at the 11th Annual Meeting of the Genetic Epidemiology of Parkinson's disease (GEoPD) Consortium 5-8 October 2016 2016.
- Prof. Kuivaniemi, Academic Editor for PLoS ONE 2016.
- Prof. Walzl is an associate editor of Microbes and Infection.
- Prof. Walzl reviewed for Microbes and Infection, the New England Journal of Medicine, the Lancet, Lancet Infectious Diseases, the Journal of Infection.
Expert panel or committee membership
- Prof. Mizrahi served on the Discovery Expert Group of the Bill & Melinda Gates Foundation.
- Prof. Mizrahi served on the 2017 Keystone Symposia Study Group and was appointed to the 2018 Keystone Symposia Study Group.
- Prof. Mizrahi served on the Scientific Advisory Committee of SDDC, a structure-guided drug discovery consortium, funded by the Bill & Melinda Gates Foundation, and led by the Structural Genomics Consortium at the University of Toronto.
- Prof. Mizrahi served on the Scientific Advisory Board of K-RITH, University of KwaZulu Natal.
- Prof. Mizrahi served on the Scientific Advisory Board of Innovative Medicines for Tuberculosis (iM4TB), EPFL, Switzerland.
- Prof. Mizrahi served on the National TB Think Tank.
- Prof. Mizrahi served on the Strategic Review Panel of the NHLS Grants Office.
- Prof. Warner and Prof. Mizrahi were appointed to UCT’s Institutional Biosafety Committee, with Prof. Warner serving on the Executive of this committee.
- Prof. Mizrahi served on the Visiting Scholars Fund and Visiting Lecturers Fund Committee, UCT.
- Prof. Mizrahi chaired the Executive Committee of the IDM, UCT.
- Prof Mizrahi chaired the Membership Committee of the IDM, UCT.
- Prof. Warner chaired the Health & Safety Committee of the IDM, UCT.
- Prof. Warner chaired the Faculty of Health Sciences Biosafety Committee, UCT.
- Prof. Warner served as the MMRU Hazardous Chemical Coordinator, IDM, UCT.
- Prof. Warner served on the Education Task Team and Equipment Task Team of the IDM, UCT.
- Dr. Evans served on the Health & Safety Committee of the IDM, UCT.
- Dr. Mashabela served on the Operations and Administration Committee of the IDM, UCT.
- Prof. Kana served on the Scientific Advisory Committee of the Cape Town HVTN Immunology Laboratory.
- Prof. Kana served on the Board of the Sydney Brenner Institute for Molecular Biosciences.
- Prof. Kana served on the Board of the Microscopy and Microanalysis Unit at Wits University.
- Prof. Kana served as a member of the Global Alliance for TB Drug Development Working Group on New TB Drugs.
- Prof. Kana and Dr. Gordhan served on the Faculty Research Council (FRC), Faculty of Health Sciences, Wits University.
- Dr. Gordhan served as chair of the Research Entity Review Task Group, Faculty of Health Sciences, Wits UniversityProf. Kana served on the FRC Budget Task Group, Faculty of Health Sciences Wits University.
- Prof. Kana served on the Advisory Board for the Faculty of Health Sciences, Wits University.
- Prof. Kana served on the Executive Committee of the School of Pathology, Faculty of Health Sciences, Wits University.
- Prof. Kana served on the Research Entity Forum, Faculty of Health Sciences, Wits University.
- Prof. Kana served on the Faculty of Health Sciences Research Equipment Review Committee, Wits University.
- Prof. Kana served on the URC major and minor Equipment Review Committees, Wits University.
- Prof. Kana served on the Faculty of Health Sciences Imaging Committee, Wits University.
- Prof. Tromp participated as Scientific Advisory Board, H3ABioNet for the H3ABioNet is a pan-African bioinformatics network in support of the the H3Africa program. H3ABioNet annual general meeting held at River Club in Observatory, November 1 and 2, 2016.
- Prof. Tab participated as Chair of HUPO-PSI Quality Control Working Group for the Human Proteomics Organization Proteomics Standards Initiative in 2016.
- Dr. Jackson etc. participated as Safety Task Team for Field Staff for the Stellenbosch University in 2016.
- Dr. Werely participated as Human Research Ethhics Committee for the Stellenbosch University Faculty of Medicine & Health Sciences in 2016.
- Dr. Chegou participated as Junior Executive member for the South African Society for Immunology (SAIS) in 2016.
- Dr. Chegou participated as Member: Health Research Ethics Committee for the Stellenbosch University in 2016.
- Profs. Miller van Helden PD, Hoal E, Dr. Parsons, outside committee members participated as South African Wildlife TB STudy Group for the Stellenbosch University, University of Pretoria, SANParks, EKZN Wildlife, DAFF in 2016.
- Prof. Miller participated as U.S. Animal Health Association TB Scientific Advisory Subcommittee for the U.S. Animal Health Association in 2016.
- Prof. Miller participated as U.S. Animal Health Association Committe on TB for the U.S. Animal Health Association in 2016.
- Ms. Pule participated as Ambassador of the South African National Tuberculosis Association (SANTA) for the The South African National Tuberculosis Association (SANTA) in 2016.
- Ms. Pule participated as Chief Executive Officer of the Caroline Pule Science and Literacy Foundation (CPSLF) for the The Caroline Pule Science and Literacy Foundation (CPSLF) in 2016.
- Prof. Bardien participated as Member of Health Sciences Specialist Committee for Rating Researchers for the National Research Foundation Rating; 2013 - 2016 in 2016.
- Prof. Sampson is a member of the Faculty Research sub-com C and SU Biosafety and Environmental Ethics committee.
- Ms. Pule served on the Selection committee for 2016 Angus Honours Scholarship co-ordinated by SAWISE
- Prof. Walzl served as voting member of the TB Scientific Committee of the IMPAACT network
- Prof. Walzl is a peer review committee member of the FDA, NIAID and BMGF-funded Consortium for TB Biomarkers (CTB2)
- Prof. Mizrahi, Prof. Kana and Prof. Walzl contribute to the SAMRC initiated TB Think Tank, which serves in an advisory capacity to the Department of Health
- Prof. Walzl serves on the Faculty of Medicine and Health Sciences Research Committee
- Prof. Walzl serves on the SU research committee, where he represents his faculty
- Prof. Walzl chairs the Division of Molecular Biology and Human Genetics Management Committee at his faculty
- Prof. Walzl chairs the Department of Biomedical Sciences Steering Committee at his faculty
- Prof. Walzl serves on the External Advisory Board of the TB Sequel project, a BMBF (German Ministry for Education and Science) funded initiative for “Research Networks on Health Innovations in sub-Saharan Africa”, led by Dr Gavin Churchyard and Dr Michael Hoelscher.
- Prof. Mizrahi served as Co-Chair of TB2016, International AIDS Society Conference, Durban July 2016. This conference also served as the fourth South African TB Conference.
Selection of research funding reviews
- Prof. Mizrahi served as a reviewer of research and fellowship applications for the HHMI; the Fondation pour la Recherche Medicale (France), Institut Pasteur and the NRF (IEPD program), and as reviewer for promotions at the Crick Institute and Tsingua University (Beijing).
- Prof. Warner served as reviewer for international funding organizations including the Wellcome Trust (UK), and the Africa Research Excellence Fund (AREF) College of Experts (AREF). He was also a reviewer for major South African funding organizations (NRF, MRC) and the various programmes they administer, including competitive funding for un/rated researchers, and MRC self-initiated research grants, and NRF student funding applications. In addition, he served as an internal reviewer for numerous research proposals considered by the IDM Research Committee, the Human Research Ethics Committee, and the Faculty Biosafety Committee. Prof. Warner also served as reviewer of applications for the International Union against Tuberculosis and Lung Disease Conference, 2016.
- Members of the CBTBR Wits node reviewed for the NHLS Research Trust, Biotechnology and Biological Sciences Research Council (BBSRC, UK), South African Medical Research Council (various programs), Soweto Matlosana Collaborating Centre for HIV and TB (SoMCHAT), the NHLS Research Trust, and the National Research Foundation (Rating and Evaluation Program).
- Members of the Wits node of the CBTBR served on the following panels, selection committees:
- Interview panel for the Diversifying of the Academy post of Lecturer, School of Pathology, Wits
- MSc protocol assessment - assessed 5 MSc. protocols, Faculty of Health Sciences, Wits.
- Application for general release of genetically modified organisms – poultry vaccine for Department of Agriculture, Forestry and Fisheries (DoAFF).
- Poster session judge for the Faculty of Health sciences at the 7th cross-faculty postgraduate symposium, Wits (Judged 17 posters).
- The BTC selection committee. Assessed 12 bursary applications.
- Prof. Walzl reviewed applications for the BMGF, the Wellcome Trust and the NRF
- Prof. Walzl acted as reviewer for a senior appointment at the University of Pennsylvania.
- Members of the SU node of the CBTBR served on the following panels, selection committees:
- Interview panels for promotion to Associate or Full Professor posts at SU
- MSc protocol assessments, Faculty of Medicine and Health Sciences, SU.
- PhD protocol assessments, Faculty of Medicine and Health Sciences, SU.
Beneficiation of other researchers by CBTBR
The SUN node also provides infrastructure and intellectual support to groups, even some who are not TB researchers and are therefore defined to be completely outside the CBTBR. For example, the lab housing the CBTBR genetics group also hosts a small group of lab researchers, mostly students working on the Genetics of Psychiatric Disorders, part of the NRF SARCHi research of Prof. Seedat. It also houses a small SUN group (Prof. Bardien) working on the genetics of Parkinsons disease in South Africans, and from time to time hosts a research student working on diseases of the prostate from the division of Urology. All of the PIs involved have or have had NRF support. They are also fully integrated with three SU based TB SARChI’s and their researchers and students. A UCT based SARhI (Prof. Dheda) and his team also utilise CBTBR facilities. Other researchers within SU, such as numerous persons from Paediatrics, Medical Microbiology and Immunology also use CBTBR facilities. The SU BL3 lab has approximately 70 registered users, of whom about 50 are part of the SU CBTBR node.
The UCT node is an integral component of the Institute of Infectious Disease and Molecular Medicine (IDM) and a major contributor to the institute’s shared research capacity and infrastructure, which is of direct benefit to all member groups involved in TB research. This includes a shared BSL3 laboratory, in which the UCT node has invested considerable resource. This laboratory serves the needs of 41 registered and 38 trainee users from across the IDM, only 12 of whom are supported directly by the CBTBR. The UCT node also provides extensive technical support and assistance in all aspects of mycobacteriology to staff, students and postdocs from the groups of three SARChI chairs, the Clinical Infectious Disease Research Initiative (CIDRI, recently incorporated into the Wellcome Centre for Clinical Infectious Disease Research in Africa), the Desmnod Tutu HIV Centre and the SA TB Vaccine Initiative (SATVI). The only outputs reported herein from the UCT node are those funded directly by the NRF grant to the CoE and resulting from the research and training programmes led by the two Team Members in this node, Prof. Mizrahi and Prof. Warner, and the member of the Scientific Staff, Dr. J Evans. However, Prof. Mizrahi and Prof. Warner have been major contributors to two new initiatives in the IDM and UCT Faculty of Health Sciences. First, Prof. Mizrahi is a PI and BSL3 Platform Lead of CIDRI-Africa, the first Wellcome Trust Centre established at a university outside the UK. Second, Prof. Warner has jointly led the establishment of an advanced Confocal and Superresolution Microscopy Facility in the UCT Faculty of Health Sciences, with funding from the Wellcome Trust, the NRF (NEP) and the Wolfson Foundation.
Other services rendered
The SU immunology group performs QFT tests for Tygerberg Academic Hospital, including special clinical diagnostic challenges and for visiting students and staff from low-TB endemic countries.